Izzie's break from Grey's

From Ausiello : When asked if the rumours that Izzie was going to cheat on Alex were true, he answered "No, but the newlyweds will be dealt a major blow at the end of next week’s episode (the best of the season, IMHO). In fact, the crisis is so big that Izzie disappears for roughly five non-consecutive episodes. BTW, even though I knew Katherine Heigl’s mini-hiatus was coming, Izzie’s exit was no less powerful or emotional. And man, Heigl knocks it out of the park. She can be a real handful (see: Emmygate, 17-hour workdaygate, etc) but girlfriend delivers when it’s called for."
As for Ellen Pompeo's maternity leave, he adds : "Unlike Izzie, Meredith isn’t going anywhere — although we’ll begin to see less of her (literally and figuratively) after this week’s episode. And her diminished screen time will make perfect sense given what happens tomorrow night."

I agree about Katherine Heigl ! To me, she's the best one of the best on the cast and you can throw pretty much anything at her, she'll excell !! I can't wait to know what happens that makes her leave !! The good news is it's only for 5 non-consecutive episodes ! If she's only out for 5 episodes out of the entire season, it's all good for me !!